Update in Intensive Care and Emergency Medicine: Proceedings by N. C. Staub (auth.), Dr. J. L. Vincent (eds.)

By N. C. Staub (auth.), Dr. J. L. Vincent (eds.)

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Intermittent mandatory ventilation, IMV, can avoid many of these problems. IMV will permit unrestricted, unassisted spontaneous ventilation to occur between mechanical breaths, which may be applied at a rate just sufficient to prevent respiratory acidemia. By maintaining spontaneous ventilation, alterations in inspired gas distribution and physiologic dead-space volume are minimized. In addition, it is possible to maintain normal alveolar minute ventilation without sedatives, muscle relaxants, addition of dead-space, carbon dioxide, or any combination of these.

Ward PA (1983) Role of toxic oxygen products from phagocytic cells in tissue injury. Adv in Shock Res 10:27-34 Physiological Effects of Increased Airway Pressure J. B. Downs Clinicians frequently adopt an imperical approach to the respiratory care of patients with pulmonary failure. As a result, only the symptomatology is treated, which often fails to restore normal pulmonary function and may have deleterious side effects. Since therapeutic interventions may have significant physiologic consequences, rational application of therapies requires an understanding of the variable physiologic effects of different ventilatory patterns.

Clin Sci Molec Med 52:395 14. Starling EH (1912) Principles of Human Physiology, 1st ed. Lea & Febiger, Philadelphia 15. Arora NS, Rochester DF (1977) Effect of general nutritional and muscular states on the human diaphragm. Am Rev Respir Dis 115 :84 16. Braude-Heller A, Ratbalsam J, Eibinger R (1946) Clinique de Ia famine chez les enfants, pp 173-187. In: Appelbaum E (ed) Quoted in Keys et aI, p 602 17. Garbagni R, Coppo F, Gassini G, et al (1968) Effects of lipid loading and fasting on pulmonary surfactant.

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