By Jacqueline J. Coalson, Richard D. Bland
content material: advent / Claude Lenfant --
half One. medical features --
ancient standpoint : Early Observations and next Evolution of Bronchopulmonary Dysplasia / William H. Northway, Jr. --
Epidemiology of Bronchopulmonary Dysplasia : medical hazard elements and linked medical stipulations / Alma Martinez, Peter Dargaville, H. William Taeusch --
medical direction and Lung functionality Abnormalities in the course of improvement of Neonatal continual Lung illness / Eduardo Bancalari, Alvaro Gonzalez --
Radiographic gains of BPD and capability program of recent Imaging options / David okay. Edwards, William H. Northway, Jr. --
Pathology of persistent Lung illness of Early Infancy / Jacqueline J. Coalson --
The Usefulness of Bronchoalveolar Lavage in babies with Evolving persistent Lung ailment / Carl W. White, Leland L. Fan --
Inflammatory Mediators in Neonatal Lung sickness / Christian P. Speer, Peter Groneck --
an infection within the Pathogenesis of Bronchopulmonary Dysplasia / William E. Benitz, Ann M. Arvin --
air flow innovations and Bronchopulmonary Dysplasia / W. Alan Hodson --
influence of respiration Care Practices at the improvement of Bronchopulmonary Dysplasia / Michael R. Gomez, Thomas N. Hansen --
effect of Surfactant substitute on improvement of Bronchopulmonary Dysplasia / Alan H. Jobe --
Drug therapy for verified BPD / Thomas A. Hazinski --
dietary matters in persistent Lung disorder of untimely babies / Ilene R.S. Sosenko, Michael T. Kinter, Robert J. Roberts --
Pulmonary functionality in BPD and Its Aftermath / Eric C. Eichenwald, Ann R. Stark --
Cardiovascular Abnormalities in Bronchopulmonary Dysplasia / Michael Apkon, Rodrigo A. Nehgme, George Lister --
long term restoration from Bronchopulmonary Dysplasia / Solomon Alkrinawi, Victor Chernick --
The aim : Prevention of BPD / Mildred T. Stahlman --
half . basic and irregular Alveolar and Airway improvement --
special positive factors of the Immature Lung That Make It prone to harm / Scott H. Randell, Stephen L. younger --
Hormonal results on Lung Maturation and ailment / Philip L. Ballard, Roberta A. Ballard --
Mechanisms and Physiological Sequelae of Reactive Species damage to the Alveolar Epithelium / Imad Y. Haddad ... [et al.] --
Surfactant in continual Lung harm / Richard J. King, Samuel Hawgood --
The rules of the Formation of Pulmonary Alveoli / Donald J. Massaro, Gloria D. Massaro --
elements Mediating mobile progress in Lung harm / A. Keith Tanswell ... [et al.] --
Developmental Airway constitution and serve as in wellbeing and fitness and protracted Lung damage / Howard B. Panitch, Thomas H. Shaffer --
half 3. basic and irregular improvement of the Lung movement and Interstitium --
Lung improvement and the results of power Hypoxia / Sheila G. Haworth --
Altered improvement of the Pulmonary move in power Lung damage / Marlene Rabinovitch --
Pulmonary high blood pressure in persistent Lung affliction of Infancy: Pathogenesis, Pathophysiology, and remedy / Steven H. Abman --
Connective Tissues in Lung improvement and ailments in Early Infancy / David J. Riley --
Pulmonary Edema After untimely start : development from Acute to persistent Lung disorder / Richard D. Bland, David P. Carlton --
half 4. Mechanisms of Lung damage and service in the course of improvement --
Molecular Mechanisms of Oxygen-Induced Lung harm / Charles Vincent Smith, Stephen E. Welty --
overview of Tissue damage from Reactive Oxygen Metabolites / Michael J. Thomas, Timothy W. Robinson, Henry Jay Forman --
continual Lung sickness of Early Infancy : function of Neutrophils / Diane E. Lorant, Kurt Albertine, John F. Bohnsack --
The function of Pulmonary Macrophages in continual Lung disorder of Early Infancy / Michael P. Sherman, William E. Truog --
Oxidants and Antioxidants : What function Do They Play in continual Lung sickness? / H. Lee Frank, Ilene R.S. Sosenko --
Proteolytic Enzymes and Their Inhibitors in Lung health and wellbeing and affliction / John R. Hoidal, Mari okay. Hoidal --
web site- and Mechanism-Directed Interventions for Tissue unfastened Radical harm / William R. Berrington ... [et al.] --
half 5. versions of Lung damage and service in the course of improvement --
Genetic types for the research of Autocrine-Paracrine Signaling in Lung improvement and service / Jeffrey A. Whitsett --
Animal types of continual Lung damage / Jacqueline J. Coalson ... [et al.].
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Extra resources for Chronic lung disease in early infancy
In a study of human leukocyte antigens (HLA) in 101 newborn infants, Hafez et al. (22) found that carriage of HLA-A3 and B14 was associated with greater risk of RDS. Twin studies have demonstrated a greater concordance for RDS in monozygotic than in dyzygotic twins, although obstetrical factors may confound this association (23). Several studies examining the role of familial factors in predispositon to RDS have noted a higher incidence of RDS in siblings of an index case than in siblings of an infant with no lung disease (24–26).
However, permanent changes of BPD on chest radiographs may be seen in older children and young adults. These changes are typically subtle and consist primarily of peribronchial cuffing, focal and diffuse linear densities, hyperexpansion, pleural scarring, and occasional pectus carinatum or excavatum deformities (97,100). High-resolution computed tomography (CT) scans of the lungs of children and young adults with prior BPD can demonstrate septal thickening, areas of focal increased lucency that may represent either persistent emphysema or focal areas of air trapping, and vascular remodeling (101,102).
Treatment of the ideopathic respiratory distress syndrome with continuous positive airway pressure. N Engl J Med 1971; 284:1333–1378. Avery ME, Merritt TA. Surfactant-replacement therapy. N Engl J Med 1991; 324: 910–911. Parker RA, Lindstrom DP, Cotton RB. Improved survival accounts for most, but not all, of the increase in bronchopulmonary dysplasia. Pediatrics 1992; 90:663– 668. Muraskas JK, Carlson NJ, Halsey C. Survival of a 280 gm infant. N Engl J Med 1991; 324:1598. Northway WH Jr. Bronchopulmonary dysplasia: twenty five years later.