By Nomivama H., Yoshie O.
CCR7. often referred to as Epstein-Barr virw-y-induced gene 1 (EBI1) or Burkitt's lymphoma receptor 2 (BLR2>. used to be initially pointed out as an orphan G protein-coupled receptor. Later, it was once discovered to be a receptor for the CC chemokines ELC/MIP-3tf and SLC, 6Ckine. CCR7 is principally expressed on lymphocytes and dendritic cells, and is critical in migration of those different types of cells to secondary lymphoid tissues. CCR7 can also be all in favour of viral pathogenesis because the expression of CCR7 is upregulated by means of an infection of lymphocytes and dendritic cells, and is necessary in migration of those kinds of cells to secondary lymphoid tissues. CCR7 can also be concerned about viral pathogenesis because the expression of CCR7 is upregulated through an infection of dendritic cells, and is necessary in migration of those mobile kinds to secondary lymphoid tissues. CCR7 can also be fascinated by viral pathogenesis because the expression of CCR7 is upregulated by way of an infection of cells with Epstein-В orr virus (EBV) and T cells with /n/man herpesvirus (HHV) kinds 6 and seven. The human gene for CCR7 is found on human chromosome 17cj 12-u.21.2.
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